/* ===========================================
   Blood Test Analyzer - Main Stylesheet
   =========================================== */

/* Reset & Base */
* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

:root {
    /* Colors */
    --primary-color: #2563eb;
    --primary-hover: #1d4ed8;
    --success-color: #10b981;
    --warning-color: #f59e0b;
    --danger-color: #ef4444;
    --text-primary: #111827;
    --text-secondary: #6b7280;
    --border-color: #e5e7eb;
    --bg-light: #f9fafb;
    --bg-white: #ffffff;
    
    /* Spacing */
    --spacing-xs: 0.5rem;
    --spacing-sm: 1rem;
    --spacing-md: 1.5rem;
    --spacing-lg: 2rem;
    --spacing-xl: 3rem;
    
    /* Typography */
    --font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif;
    --font-size-sm: 0.875rem;
    --font-size-base: 1rem;
    --font-size-lg: 1.125rem;
    --font-size-xl: 1.25rem;
    --font-size-2xl: 1.5rem;
    --font-size-3xl: 1.875rem;
    
    /* Border Radius */
    --radius-sm: 0.375rem;
    --radius-md: 0.5rem;
    --radius-lg: 0.75rem;
    
    /* Shadows */
    --shadow-sm: 0 1px 2px 0 rgba(0, 0, 0, 0.05);
    --shadow-md: 0 4px 6px -1px rgba(0, 0, 0, 0.1);
    --shadow-lg: 0 10px 15px -3px rgba(0, 0, 0, 0.1);
}

body {
    font-family: var(--font-family);
    font-size: var(--font-size-base);
    line-height: 1.6;
    color: var(--text-primary);
    background-color: var(--bg-light);
}

/* ===========================================
   Typography
   =========================================== */

h1, h2, h3, h4, h5, h6 {
    font-weight: 600;
    line-height: 1.2;
    margin-bottom: var(--spacing-sm);
}

h1 { font-size: var(--font-size-3xl); }
h2 { font-size: var(--font-size-2xl); }
h3 { font-size: var(--font-size-xl); }
h4 { font-size: var(--font-size-lg); }

p {
    margin-bottom: var(--spacing-sm);
}

a {
    color: var(--primary-color);
    text-decoration: none;
    transition: color 0.2s;
}

a:hover {
    color: var(--primary-hover);
}

/* ===========================================
   Layout Components
   =========================================== */

.container {
    max-width: 1200px;
    margin: 0 auto;
    padding: 0 var(--spacing-md);
}

.container-narrow {
    max-width: 800px;
    margin: 0 auto;
    padding: 0 var(--spacing-md);
}

/* Header */
.header {
    background-color: var(--bg-white);
    border-bottom: 1px solid var(--border-color);
    padding: var(--spacing-md) 0;
    box-shadow: var(--shadow-sm);
}

.header-content {
    display: flex;
    justify-content: space-between;
    align-items: center;
}

.logo {
    font-size: var(--font-size-xl);
    font-weight: 700;
    color: var(--primary-color);
}

.nav {
    display: flex;
    gap: var(--spacing-md);
}

.nav a {
    padding: var(--spacing-xs) var(--spacing-sm);
    border-radius: var(--radius-sm);
    transition: background-color 0.2s;
}

.nav a:hover {
    background-color: var(--bg-light);
}

/* Main Content */
.main {
    padding: var(--spacing-xl) 0;
    min-height: calc(100vh - 200px);
}

/* Footer */
.footer {
    background-color: var(--bg-white);
    border-top: 1px solid var(--border-color);
    padding: var(--spacing-lg) 0;
    margin-top: var(--spacing-xl);
    text-align: center;
    color: var(--text-secondary);
    font-size: var(--font-size-sm);
}

/* ===========================================
   Cards
   =========================================== */

.card {
    background-color: var(--bg-white);
    border-radius: var(--radius-lg);
    box-shadow: var(--shadow-md);
    padding: var(--spacing-lg);
    margin-bottom: var(--spacing-md);
}

.card-header {
    border-bottom: 1px solid var(--border-color);
    padding-bottom: var(--spacing-sm);
    margin-bottom: var(--spacing-md);
}

.card-title {
    font-size: var(--font-size-xl);
    font-weight: 600;
    margin: 0;
}

.card-subtitle {
    font-size: var(--font-size-sm);
    color: var(--text-secondary);
    margin-top: var(--spacing-xs);
}

/* ===========================================
   Forms
   =========================================== */

.form-group {
    margin-bottom: var(--spacing-md);
}

.form-label {
    display: block;
    font-weight: 500;
    margin-bottom: var(--spacing-xs);
    color: var(--text-primary);
}

.form-label-required::after {
    content: " *";
    color: var(--danger-color);
}

.form-input,
.form-select,
.form-textarea {
    width: 100%;
    padding: var(--spacing-xs) var(--spacing-sm);
    border: 1px solid var(--border-color);
    border-radius: var(--radius-md);
    font-size: var(--font-size-base);
    transition: border-color 0.2s, box-shadow 0.2s;
}

.form-input:focus,
.form-select:focus,
.form-textarea:focus {
    outline: none;
    border-color: var(--primary-color);
    box-shadow: 0 0 0 3px rgba(37, 99, 235, 0.1);
}

.form-textarea {
    resize: vertical;
    min-height: 100px;
}

.form-help {
    font-size: var(--font-size-sm);
    color: var(--text-secondary);
    margin-top: var(--spacing-xs);
}

.form-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: var(--spacing-md);
}

.form-grid-2 {
    display: grid;
    grid-template-columns: 2fr 1fr;
    gap: var(--spacing-md);
}

/* ===========================================
   Buttons
   =========================================== */

.btn {
    display: inline-block;
    padding: var(--spacing-xs) var(--spacing-md);
    font-size: var(--font-size-base);
    font-weight: 500;
    text-align: center;
    border: none;
    border-radius: var(--radius-md);
    cursor: pointer;
    transition: all 0.2s;
}

.btn-primary {
    background-color: var(--primary-color);
    color: white;
}

.btn-primary:hover {
    background-color: var(--primary-hover);
    transform: translateY(-1px);
    box-shadow: var(--shadow-md);
}

.btn-secondary {
    background-color: var(--bg-light);
    color: var(--text-primary);
    border: 1px solid var(--border-color);
}

.btn-secondary:hover {
    background-color: var(--border-color);
}

.btn-success {
    background-color: var(--success-color);
    color: white;
}

.btn-danger {
    background-color: var(--danger-color);
    color: white;
}

.btn-lg {
    padding: var(--spacing-sm) var(--spacing-lg);
    font-size: var(--font-size-lg);
}

.btn-block {
    display: block;
    width: 100%;
}

/* ===========================================
   Badges & Status
   =========================================== */

.badge {
    display: inline-block;
    padding: 0.25rem 0.75rem;
    font-size: var(--font-size-sm);
    font-weight: 500;
    border-radius: var(--radius-sm);
}

.badge-success {
    background-color: #d1fae5;
    color: #065f46;
}

.badge-warning {
    background-color: #fed7aa;
    color: #92400e;
}

.badge-danger {
    background-color: #fee2e2;
    color: #991b1b;
}

.status-favorable {
    color: var(--success-color);
    font-weight: 600;
}

.status-watch {
    color: var(--warning-color);
    font-weight: 600;
}

.status-elevated {
    color: var(--danger-color);
    font-weight: 600;
}

/* ===========================================
   Tables
   =========================================== */

.table-wrapper {
    overflow-x: auto;
    margin: var(--spacing-md) 0;
}

.table {
    width: 100%;
    border-collapse: collapse;
}

.table th,
.table td {
    padding: var(--spacing-sm);
    text-align: left;
    border-bottom: 1px solid var(--border-color);
}

.table th {
    font-weight: 600;
    background-color: var(--bg-light);
}

.table tbody tr:hover {
    background-color: var(--bg-light);
}

/* ===========================================
   Alerts & Messages
   =========================================== */

.alert {
    padding: var(--spacing-md);
    border-radius: var(--radius-md);
    margin-bottom: var(--spacing-md);
}

.alert-success {
    background-color: #d1fae5;
    border-left: 4px solid var(--success-color);
    color: #065f46;
}

.alert-warning {
    background-color: #fed7aa;
    border-left: 4px solid var(--warning-color);
    color: #92400e;
}

.alert-error {
    background-color: #fee2e2;
    border-left: 4px solid var(--danger-color);
    color: #991b1b;
}

.alert-info {
    background-color: #dbeafe;
    border-left: 4px solid var(--primary-color);
    color: #1e40af;
}

#error-message,
#success-message {
    display: none;
}

/* ===========================================
   Loading Spinner
   =========================================== */

.loading {
    display: none;
    position: fixed;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background-color: rgba(0, 0, 0, 0.5);
    justify-content: center;
    align-items: center;
    z-index: 9999;
}

.spinner {
    border: 4px solid var(--bg-light);
    border-top: 4px solid var(--primary-color);
    border-radius: 50%;
    width: 50px;
    height: 50px;
    animation: spin 1s linear infinite;
}

@keyframes spin {
    0% { transform: rotate(0deg); }
    100% { transform: rotate(360deg); }
}

/* ===========================================
   Hero Section
   =========================================== */

.hero {
    text-align: center;
    padding: var(--spacing-xl) 0;
}

.hero-title {
    font-size: 3rem;
    margin-bottom: var(--spacing-md);
}

.hero-subtitle {
    font-size: var(--font-size-xl);
    color: var(--text-secondary);
    margin-bottom: var(--spacing-lg);
}

.hero-actions {
    display: flex;
    gap: var(--spacing-md);
    justify-content: center;
}

/* ===========================================
   System Panels
   =========================================== */

.system-panels {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
    gap: var(--spacing-md);
    margin-top: var(--spacing-lg);
}

.system-panel {
    background-color: var(--bg-white);
    border-radius: var(--radius-lg);
    box-shadow: var(--shadow-md);
    padding: var(--spacing-md);
}

.system-panel-header {
    display: flex;
    justify-content: space-between;
    align-items: center;
    margin-bottom: var(--spacing-sm);
}

.system-panel-title {
    font-size: var(--font-size-lg);
    font-weight: 600;
}

.system-panel-drivers {
    margin-top: var(--spacing-md);
}

.driver-item {
    display: flex;
    flex-direction: column;
    padding: var(--spacing-sm);
    margin-bottom: var(--spacing-xs);
    border-radius: var(--radius-sm);
    background-color: var(--bg-light);
}

.driver-item:last-child {
    margin-bottom: 0;
}

.driver-info {
    display: flex;
    justify-content: space-between;
    align-items: center;
}

.driver-name {
    font-weight: 500;
}

.driver-value {
    font-weight: 700;
}

.driver-interpretation {
    font-size: var(--font-size-sm);
    color: var(--text-secondary);
    margin-top: 0.25rem;
}

/* Driver status colors */
.driver-item.driver-normal {
    background-color: var(--bg-light);
}

.driver-item.driver-normal .driver-value {
    color: var(--text-primary);
}

.driver-item.driver-warning {
    background-color: #fef3c7;
    border-left: 3px solid var(--warning-color);
}

.driver-item.driver-warning .driver-name,
.driver-item.driver-warning .driver-value {
    color: #92400e;
}

.driver-item.driver-warning .driver-interpretation {
    color: #a16207;
}

.driver-item.driver-danger {
    background-color: #fee2e2;
    border-left: 3px solid var(--danger-color);
}

.driver-item.driver-danger .driver-name,
.driver-item.driver-danger .driver-value {
    color: #991b1b;
}

.driver-item.driver-danger .driver-interpretation {
    color: #b91c1c;
}

/* Driver Recommendations */
.driver-recommendations {
    margin-top: var(--spacing-xs);
    font-size: var(--font-size-sm);
}

.driver-recs-toggle {
    cursor: pointer;
    font-weight: 500;
    padding: 0.25rem 0;
    user-select: none;
}

.driver-recs-toggle:hover {
    text-decoration: underline;
}

.driver-recs-list {
    margin: var(--spacing-xs) 0 0 1.25rem;
    padding: 0;
    line-height: 1.5;
}

.driver-recs-list li {
    margin-bottom: 0.25rem;
}

.driver-item.driver-warning .driver-recs-toggle {
    color: #92400e;
}

.driver-item.driver-danger .driver-recs-toggle {
    color: #991b1b;
}

.driver-item.driver-warning .driver-recs-list {
    color: #78350f;
}

.driver-item.driver-danger .driver-recs-list {
    color: #7f1d1d;
}

/* ===========================================
   Results Display
   =========================================== */

.result-summary {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
    gap: var(--spacing-md);
    margin-bottom: var(--spacing-lg);
}

.result-card {
    text-align: center;
    padding: var(--spacing-md);
    background-color: var(--bg-white);
    border-radius: var(--radius-lg);
    box-shadow: var(--shadow-sm);
}

.result-label {
    font-size: var(--font-size-sm);
    color: var(--text-secondary);
    margin-bottom: var(--spacing-xs);
}

.result-value {
    font-size: var(--font-size-3xl);
    font-weight: 700;
    color: var(--primary-color);
}

.result-unit {
    font-size: var(--font-size-lg);
    color: var(--text-secondary);
}

/* ===========================================
   Responsive Design
   =========================================== */

@media (max-width: 768px) {
    .hero-title {
        font-size: 2rem;
    }
    
    .hero-actions {
        flex-direction: column;
    }
    
    .form-grid {
        grid-template-columns: 1fr;
    }
    
    .form-grid-2 {
        grid-template-columns: 1fr;
    }
    
    .result-summary {
        grid-template-columns: 1fr;
    }
}

/* ===========================================
   Utility Classes
   =========================================== */

.text-center { text-align: center; }
.text-right { text-align: right; }
.text-muted { color: var(--text-secondary); }
.text-small { font-size: var(--font-size-sm); }
.text-bold { font-weight: 600; }

.mt-1 { margin-top: var(--spacing-sm); }
.mt-2 { margin-top: var(--spacing-md); }
.mt-3 { margin-top: var(--spacing-lg); }
.mb-1 { margin-bottom: var(--spacing-sm); }
.mb-2 { margin-bottom: var(--spacing-md); }
.mb-3 { margin-bottom: var(--spacing-lg); }

.d-flex { display: flex; }
.d-none { display: none; }
.gap-1 { gap: var(--spacing-sm); }
.gap-2 { gap: var(--spacing-md); }
.justify-between { justify-content: space-between; }
.align-center { align-items: center; }

.text-success { color: var(--success-color); }
.text-danger { color: var(--danger-color); }
.text-warning { color: var(--warning-color); }

/* ===========================================
   Biomarker Impact Analysis
   =========================================== */

.biomarker-impact-grid {
    display: flex;
    flex-direction: column;
    gap: var(--spacing-sm);
}

.biomarker-impact-row {
    display: grid;
    grid-template-columns: 1fr 200px 120px;
    gap: var(--spacing-md);
    align-items: center;
    padding: var(--spacing-sm);
    border-radius: var(--radius-md);
    background-color: var(--bg-light);
    transition: background-color 0.2s;
}

.biomarker-impact-row:hover {
    background-color: var(--border-color);
}

.biomarker-impact-row.impact-negative {
    background-color: #fee2e2;
}

.biomarker-impact-row.impact-watch {
    background-color: #fef3c7;
}

.biomarker-impact-row.impact-positive {
    background-color: #d1fae5;
}

.biomarker-impact-row.impact-neutral {
    background-color: var(--bg-light);
}

.biomarker-info {
    display: flex;
    flex-direction: column;
    gap: 0.25rem;
}

.biomarker-name {
    font-weight: 600;
    font-size: var(--font-size-base);
}

.biomarker-values {
    display: flex;
    gap: var(--spacing-md);
    font-size: var(--font-size-sm);
}

.actual-value {
    font-weight: 500;
}

.optimal-value {
    color: var(--text-secondary);
}

.biomarker-impact {
    display: flex;
    align-items: center;
    gap: var(--spacing-sm);
}

.impact-bar-container {
    width: 100px;
    height: 12px;
    background-color: rgba(0, 0, 0, 0.1);
    border-radius: 6px;
    position: relative;
    overflow: hidden;
}

.impact-bar {
    height: 100%;
    border-radius: 6px;
    transition: width 0.3s ease;
}

.impact-bar-right {
    background: linear-gradient(90deg, var(--warning-color), var(--danger-color));
    position: absolute;
    left: 50%;
}

.impact-bar-left {
    background: linear-gradient(90deg, var(--success-color), #34d399);
    position: absolute;
    right: 50%;
}

.impact-years {
    font-weight: 700;
    font-size: var(--font-size-sm);
    min-width: 60px;
    text-align: right;
}

.impact-years.impact-negative {
    color: var(--danger-color);
}

.impact-years.impact-watch {
    color: var(--warning-color);
}

.impact-years.impact-positive {
    color: var(--success-color);
}

.impact-years.impact-neutral {
    color: var(--text-secondary);
}

.biomarker-direction {
    font-size: var(--font-size-sm);
    color: var(--text-secondary);
    white-space: nowrap;
}

/* Biomarker Recommendations */
.biomarker-recommendations {
    margin-top: var(--spacing-xs);
    font-size: var(--font-size-sm);
}

.recommendations-toggle {
    cursor: pointer;
    color: var(--primary-color);
    font-weight: 500;
    padding: 0.25rem 0;
    user-select: none;
}

.recommendations-toggle:hover {
    text-decoration: underline;
}

.recommendations-list {
    margin: var(--spacing-xs) 0 0 1.25rem;
    padding: 0;
    color: var(--text-secondary);
    line-height: 1.6;
}

.recommendations-list li {
    margin-bottom: 0.25rem;
    padding-left: 0.25rem;
}

.biomarker-impact-row.impact-negative .recommendations-toggle,
.biomarker-impact-row.impact-watch .recommendations-toggle {
    color: #b45309;
}

.biomarker-impact-row.impact-positive .recommendations-toggle,
.biomarker-impact-row.impact-neutral .recommendations-toggle {
    color: #047857;
}

/* Responsive adjustments for biomarker impact */
@media (max-width: 768px) {
    .biomarker-impact-row {
        grid-template-columns: 1fr;
        gap: var(--spacing-xs);
    }

    .biomarker-impact {
        justify-content: flex-start;
    }

    .biomarker-direction {
        display: none;
    }
}